Introduction
Diagnosis of Thalassemia
Transfusion Therapy
• General Recommendations
• Transfusion Administration
• Alloantibodies and Autoantibodies
• Splenectomy
Iron Overload and Chelation Therapy
• Initiation of Chelation
• Treatment with Desferrioxamine
• Patients w/ Significant Iron Overload
• Assessment and Monitoring of Iron Overload
• Table I
• Assessment of Desferrioxamine Toxicity
Liver Disease
• Screening for Hepatic Dysfunction
• Monitoring of Patients with Hepatic Dysfunction
• Evaluation for Hepatitis C
• Evaluation and Treatment for Hepatitis B
Endocrine Dysfunction
• Routine Endocrine Screening Page 15
• Specific Endocrinopathies: Testing and Evaluation Page 15
• Diabetes Page 15
• Osteoporosis Page 16
• Growth Hormone Deficiency Page 16
• Hypogonadism Page 17
• Hypothyroidism Page 17
• Hypoparathyroidism Page 18
• Adrenal Insufficiency Page 18
Cardiac Dysfunction
• Cardiac Evaluation
• Echocardiography Standards
• Treatment of Heart Failure and Pulmonary Hypertension
Bone Marrow Transplantation
• Iron Overload after a BMT
Other Systems
• Dental Evaluation
• Nutrition
• Vaccinations
Thalassemia Intermedia
• Non-transfused Thalassemia Intermedia
Psychosocial Support
• Child Life Services
• Psychological Services
• Social Services
• Genetic Counseling
• Table II |
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